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Spinocerebellar ataxia (SCA) presents a formidable challenge for patients and families alike. This progressive disorder affects coordination, balance, and speech, gradually weakening quality of life. While there is currently no solution for SCA, a range of treatment strategies are available to mitigate symptoms and improve overall well-being. Occu
Importantly, white subject lesions on MRI usually signify leukodystrophies, but late-onset conditions might absence these, leading to misdiagnosis [36,37,38] and may add to your overestimation of HSP cases. As there is no efficient HSP treatment, progress in leukodystrophy therapies offer hope for improvements [33, 34]. Early differentiation betwee
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